What is DSIP?

DSIP stands for Delta Sleep-Inducing Peptide. It is a neuropeptide that was first discovered in the 1970s. DSIP is naturally produced in the hypothalamus region of the brain and is involved in regulating sleep patterns and promoting deep sleep.

The DSIP is a somnogeneric peptide that impacts neuromodulation. It is typically found in the brain and passes by the blood barriers quite quickly. Studies have shown that DSIP and as well as its analogs are classified as peptide neuromodulators.

Studies have also shown that DSIP has exhibited a stress-protective action that helps decrease stress metabolic disorders for humans and animals. It is believed that the Delta Sleep-Inducing Peptide works in such a way that it modulates the activity of GABAergic gluta and other neuronal system too.

How does DSIP work?

Delta Sleep-Inducing Peptide (DSIP) is a neuropeptide that is naturally produced in the hypothalamus region of the brain. While the exact mechanisms of DSIP action are not fully understood, research suggests that it primarily influences sleep patterns and other physiological processes through its interactions with the central nervous system and other tissues.

Here are some proposed mechanisms of DSIP action:

1. Sleep regulation: DSIP is thought to play a role in promoting deep, restorative sleep. It may act on various neurotransmitter systems in the brain, such as the gamma-aminobutyric acid (GABA) and opioid systems, to induce and maintain sleep. DSIP may increase the duration of slow-wave sleep, which is characterized by deep, non-REM sleep stages.

2. Stress reduction: DSIP has been shown to have anxiolytic (anti-anxiety) and stress-reducing effects in animal studies. It may modulate the activity of stress-related pathways in the brain, such as the hypothalamic-pituitary-adrenal (HPA) axis, to reduce stress and promote relaxation.

3. Pain modulation: Some research suggests that DSIP may have analgesic (pain-relieving) properties. It may modulate pain perception pathways in the central nervous system, such as inhibiting the transmission of pain signals in the spinal cord, leading to pain relief.

4. Neuroprotection: DSIP has been investigated for its potential neuroprotective effects. It may help protect neurons from damage caused by oxidative stress, inflammation, and other harmful factors. DSIP may also promote neuronal survival and regeneration in certain conditions.

5. Immune regulation: DSIP may interact with the immune system and affect immune cell activity and cytokine production. It may have immunomodulatory effects, although the exact mechanisms are still being studied.

Overall, DSIP appears to exert its effects through complex interactions with various neurotransmitter systems, hormonal pathways, and cellular processes in the body. Further research is needed to fully elucidate the mechanisms of DSIP action and its potential therapeutic applications.

What you need to know:

It is not recommended to give out DSIP just before going to bed. The dose should be given during the day to help improve sleep the next night and as well as several days to come.

Dose: 5 mg/vial
Dosing Guideline:
250-500 mcg during the day or at least 2 hrs. before bed