What is Met-5 Enkephalin?

The opioid growth factor (OGF, also known as met-enkephalin)-OGF receptor (OGFr) axis works in animal and human cancer cell lines and tumors. Met-Enkephalin is a synthetic form of the naturally occurring, endogenous opioid peptide, metenkephalin, and agonist of the zeta- and delta-opioid receptor and, to a lesser extent the mu-opioid receptor.

How does Met-5 Enkephalin work?

Met-5-enkephalin, often referred to simply as Met-enkephalin, is an endogenous opioid peptide with a specific amino acid sequence that includes methionine as its fifth residue. Met-5 Enkephalin mimics its endogenous ligand and targets, binds to and activates the opioid receptors. This leads to an analgesic effect, inhibits neuropathic pain, and inhibits GI muscle contractility. Binding to the opioid growth factor receptor (OGFR; zeta-opioid receptor), enhances tissue growth and regeneration. In addition, activation of delta-opioid receptors located on a variety of immune cells may modulate the inflammatory immune response. This may inhibit the secretion of pro-inflammatory cytokines and the proliferation of leukocytes.

PATIENT BENEFIT:

IMPROVE MEMORY

Met-5-enkephalin is a versatile endogenous opioid peptide with significant benefits in pain relief, stress reduction, immune system modulation, mood enhancement, and potential therapeutic applications in various medical conditions. Its role in both the nervous and immune systems underscore its importance in maintaining homeostasis and overall health.

Dose: 20 mg/vial
Dosing Guideline: 10 mg (0.5 ml or 50 units) SC BID twice weekly (2 days/week)